I spent most of my twenties locked in an all-out war with my skin, and I lost every battle. You name an acne treatment, and I’ve slathered it on my face with reckless optimism and abandon. Retinoids, benzoyl peroxide, salicylic acid — I layered them like a chemist, convinced I was one product away from finally having the poreless, glowing skin everyone around me seemed to have.
Instead, I got perioral dermatitis: a cruel, red, flaky rash around my mouth that pleaded, Quit attacking your face, you dip.
After many frantic Google searches and an emergency dermatologist visit (where I was gently but explicitly told to “calm down”), I realized my skin barrier was holding on by a thread, and my hormonal acne wasn’t going to be bullied into submission with another round of spot treatments. I needed a different approach — one that didn’t involve me staring into the mirror every morning, whispering, What fresh hell is this? That’s when I stumbled across CLEARSTEM MINDBODYSKIN, a supplement designed to tackle hormonal acne from the inside out.
My review: Jump scare warning!
I was skeptical. I’ve taken enough “acne-fighting” supplements in my day to know that most of them just give you expensive pee. But the CLEARSTEM reviews were great, the founder story felt genuinely skin-nerd passionate, and there weren’t any toxic fillers or mystery ingredients in sight. Plus, my skin was already at rock bottom, so I figured since it’s not a topical chemical, what did I have to lose? Here’s how it went.
I started taking MINDBODYSKIN with the cautious optimism of a woman who has quite literally been burned before. My hormonal acne tends to flare up around my jawline, and after years of wrecking my skin barrier with topical, over-the-counter treatments, I needed something that would get to the root of the issue without sending me into another perioral dermatitis flare-up.


Within two weeks, my skin was noticeably calmer. No new cystic breakouts, no dramatic flare-ups, just steady skin. By week four, I had an almost shocking realization one day when I was applying my makeup: my skin was actually clear. Like, no, “this side of my face is fine, but don’t look at my jawline,” clear. Just…clear-clear. I have never in my life found a product that actually cleared my skin in under a month. It has been four weeks of testing this product, having purchased it myself and fully expecting it to be another meh addition to my routine. Instead, it did what years of prescriptions, topicals, birth control, and dietary changes failed to do.
The biggest difference? My usual PMS breakout never showed up. Normally, either side of my chin would be a disaster zone the week before my period, but this time? Nothing. My skin wasn’t just behaving…it was thriving. The redness from old breakouts faded, and my skin looked smoother and less inflamed overall. The best part? No new or continued perioral dermatitis flare-ups. This is huge for me because so many acne treatments send my skin straight into a full-blown bumpy, red rash. But with MINDBODYSKIN, my skin got clearer without any reactions.
And when I say no reactions, I mean no reactions. It’s a supplement, so with my luck, I half expected that even if it were to clear my skin it would probably also wreck my stomach, mind, weight…something. Nope. I physically feel better: more energy, more optimism, more clarity.
There are two types of MINDBODYSKIN: one with 5-HTP (a dietary supplement that raises serotonin levels in the brain) and one without it. I opted for the one without it since I’m already taking an SSRI, and I still got noticeably great mood affects.
The verdict

Call it a side-effect of clear skin, but I frankly don’t care what it is. I love this stuff and, better still, it loves me. Would I repurchase? Absolutely. In fact, I’m committing to taking it for another two months to reinforce the effects and make sure this isn’t some kind of skincare placebo dream. If you’ve been stuck in the cycle of over-treating, over-exfoliating, and over-stressing about your breakouts, MINDBODYSKIN might just be your skin’s new best friend.
CLEARSTEM MINDBODYSKIN

Pros:
- Actually cleared my skin in under a month (first product to ever do this)
Balances hormones naturally
Contains anti-inflammatory and stress-reducing ingredients- Supports gut health (a.k.a. fewer surprise breakouts from “mystery foods”)
No sketchy fillers, artificial dyes, or hormone disruptors- Doesn’t dry out or irritate skin like topical treatments
Cons:
- Takes time to see results (not an overnight miracle)
- Can cause an initial “purge” phase
- Pricey ($58.00 per bottle)
- Requires consistency — no skipping doses
MINDBODYSKIN is an anti-acne supplement designed to support hormonal balance, gut health, and skin clarity, all without the harsh side effects of prescription medications. It contains key ingredients like DIM (Diindolylmethane), vitamin B5, turmeric, and ashwagandha, all chosen for their ability to reduce excess androgens, calm inflammation, and support the body’s natural detoxification process. Unlike traditional acne treatments, which attack the skin from the outside, this one takes an inside-out approach, focusing on balancing the hormones and deficiencies that often trigger breakouts.
FAQs
What is CLEARSTEM MINDBODYSKIN?
CLEARSTEM MINDBODYSKIN is an anti-acne, hormone-balancing supplement designed to target breakouts from the inside out. Instead of harsh topical treatments that dry out the skin or prescription medications with heavy side effects, this supplement works by regulating hormones, reducing inflammation, and supporting gut health — three major causes of persistent acne.
It contains a blend of science-backed, natural ingredients that help clear skin, including:
- DIM (Diindolylmethane) – Regulates estrogen and testosterone levels to prevent hormonal breakouts
- Vitamin B5 (Pantothenic Acid) – Reduces excess oil production
- Turmeric & ALA (Alpha Lipoic Acid) – Anti-inflammatory powerhouses that calm redness and irritation
- Ashwagandha – Lowers cortisol levels (stress = breakouts)
- Bioavailable Zinc & Selenium – Supports skin healing and immune function
MINDBODYSKIN is gluten-free, dairy-free, soy-free, and non-toxic, making it a clean, holistic alternative to traditional acne treatments. It’s designed for people dealing with hormonal acne, adult acne, or inflammation-related breakouts, especially those who want a long-term, sustainable solution without harsh side effects.
Who is CLEARSTEM for?
CLEARSTEM MINDBODYSKIN is ideal for people struggling with hormonal acne, adult acne, inflammation-driven breakouts, or skin sensitivity caused by harsh acne treatments. It’s particularly great for those who:
- Have cyclical, hormonal breakouts (especially around the jawline or chin)
- Have tried topical treatments without success
- Struggle with gut health issues that contribute to skin problems
- Want a non-toxic, hormone-balancing approach to acne
How long does it take CLEARSTEM to work?
Most users start seeing initial improvements within 2-4 weeks, with skin looking calmer and breakouts reducing in frequency. Full results typically take 8-12 weeks, as the body adjusts to the hormonal balancing and anti-inflammatory effects. Some people may experience an initial purge phase in the first few weeks as toxins and excess hormones are flushed out.
Do I need a prescription for CLEARSTEM?
No, CLEARSTEM MINDBODYSKIN does not require a prescription. It’s an over-the-counter supplement made with all-natural, science-backed ingredients that support hormonal and skin health. However, if you’re on prescription medications for acne or hormonal conditions, it’s always a good idea to check with your doctor before starting a new supplement.
How much does CLEARSTEM cost?
A bottle of MINDBODYSKIN costs $58.00 and contains a 30-day supply (90 capsules, taken 3 per day). While it’s on the pricier side for supplements, it replaces the need for multiple skincare products and can help prevent costly dermatologist visits or prescription treatments. CLEARSTEM also offers bundle discounts and subscription options to save money on repeat purchases.
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